The research laboratory of Rachel Katzenellenbogen, MD is focused on human papillomavirus (HPV). HPV is a very common infection that affects more than 75 percent of the adult population. Nearly 5 percent of cancers worldwide are caused by HPV. Based on their association with cancer, different types of HPV are categorized as high-risk or low-risk.
The Katzenellenbogen Lab focuses on the host-pathogen interactions that activate oncogenic pathways and dysregulate typical cellular processes to permit cancer development and progression of HPV-associated cancers. The laboratory conducts fundamental molecular biology studies and works to link those models of disease to true pathophysiology in people.