Faculty Labs

Successful biomedical research demands collaboration among scientists with varying specialties. Faculty throughout IU School of Medicine's 25 academic departments work together to advance knowledge and treatment for patients in the world's most critical areas of medicine.

Adams Lab

In the research laboratory led by Zachary Adams, PhD, (Indianapolis) investigators are focused on improving access to high-quality clinical services for children, teens and families impacted by mental health problems and substance use—through research, clinical care and education.

Principal Investigator Zachary W. Adams, MS, PhD

Phone

Allen Lab

The Allen Laboratory (Indianapolis) is studying the tissue-level mechanisms responsible for musculoskeletal integrity in health and disease by utilizing numerous in vivo model systems that help investigators understand how disease and pharmaceutical intervention influence bone structure, cellular activity, tissue-level properties, and biomechanical properties.

Principal Investigator Matthew R. Allen, PhD

Phone (317) 274-1283

Alpini Lab

The Alpini Lab, led by Gianfranco Alpini, PhD, evaluates the regulation of cholangiocyte proliferation/damage during the progression of cholangiopathies, the chronic diseases that target intrahepatic cholangiocytes. Proliferating cholangiocytes display a neuroendocrine phenotype and secrete and respond to a number of hormones, neuropeptides and neurotransmitters in autocrine and paracrine signaling mechanisms.

Accepting Students

Alves Lab

Research in the Alves Lab (Indianapolis) focuses on the interdisciplinary development of translational technologies, treatments and techniques that can be used to have a positive impact on people’s lives. A chemical and bimolecular engineer, Nathan Alves, PhD, encourages researchers to apply engineering principles and designs to create translational technologies for clinical implementation.

Principal Investigator Nathan J. Alves, MS, PhD

Phone (317) 274-8770

Angus Lab

The laboratory of Steve Angus, PhD, is interested in understanding the changes in the protein kinase signaling network during tumor development and progression and in response to targeted therapeutics. (Indianapolis)

Principal Investigator Steve Angus, PhD

Phone (317) 274-8911

Apetoh Lab

The Apetoh lab (Indianapolis) investigates the relationships between T lymphocytes and anticancer immune responses. We are searching for novel molecular targets that can be exploited to endow T cells with superior anticancer activity.

Principal Investigator Lionel Apetoh, MSC, PhD

Phone (317) 278-9518

Accepting Students

Apostolova Lab

Dr. Apostolova’s research focuses on the early symptomatic and presymptomatic stages of Alzheimer’s disease and on the development and validation of sensitive imaging and genetic biomarkers for Alzheimer’s disease and other dementing disorders. (Indianapolis)

Principal Investigator Liana G. Apostolova, MD, MS, FAAN

Phone

Aronoff Lab

The Aronoff Lab (Indianapolis) studies host-microbial interactions with an emphasis on bacterial infections and innate immunity. Our microbiology and immunology research centers primarily on the female reproductive tract, specifically at the maternal-fetal interface during pregnancy.

Principal Investigator David M. Aronoff, MD

Phone (317) 274-8438

Arrizabalaga Lab

Current projects in the Arrizabalaga Lab (Indianapolis) involve the characterization of kinases, phosphatases and other signaling proteins involved in the process by which the parasite exits its host cell and the characterization of autophagy-related proteins in mitochondrial dynamics and parasite death.

Principal Investigator Gustavo A. Arrizabalaga, PhD

Phone (317) 278-6355

Atwood Lab

The Atwood Laboratory (Indianapolis) team is interested in how drugs of abuse, diet, stress and pain influence the behaviors of humans. The focus of the lab’s work is on the molecular mechanisms and brain circuits that are specifically impacted by these substances and experiences.

Principal Investigator Brady K. Atwood, PhD

Phone (317) 274-8917