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The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine seeks to be a leader in regenerative medicine and engineering to address health issues of national and international importance. ICRME researchers are dedicated to finding groundbreaking solutions in the fields of tissue reprogramming and infection management that may support the development of novel cell-based therapies for wound care, prosthetic and regenerative rehabilitation and military medicine.

Primary Goal

The center's primary goal is to find new solutions in the field of regenerative medicine by developing novel technologies to improve patient outcomes and quality of life. The interdisciplinary center consists of biologists, clinicians, computer scientists and engineers driven to innovate with strong data to support research in tissue nanotransfection, wound healing, inflammation and infection and materials and engineering. Clinically, chronic wound care is a major emphasis area. The Indiana University Health Comprehensive Wound Center is the clinical research arm of the ICRME, where patients can access the most advanced wound dressings and participate in clinical trials.

Conversion of fibroblast to induced neuronal cells at 4 weeks post nanoelectroporation

"We have chosen to focus our research on a very finite area of regenerative medicine and would like to make a significant contribution in the field of tissue reprogramming through the development of our tissue nanotransfection technology. Clinically, we are focused on the problem of chronic wounds and related complications. Our educational program is in the process of launching a new MS/PhD program on Regenerative Medicine and Technologies (RMAT). Industry and military partnerships help us learn needs to develop sustainable scientific solutions aimed at improving healthcare."

—Chandan K. Sen, PhD, FNAI, Director, Indiana Center for Regenerative Medicine and Engineering