Bone and muscle couple mechanical and biochemical stimulation to effect cellular responses through signal transduction. They also act as endocrine/secretory organs by releasing soluble factors, such as osteokines and myokines. The mechanobiology and muscle-bone crosstalk research team utilizes molecular, cellular, systemic and organismal level functional outcomes to investigate mutual interactions between bone and muscle. Given many physiological processes are regulated by bone and muscle in a paracrine manner, our group also investigates distant tissues in development, normal physiology and disease.
The Mechanobiology & Muscle-Bone Crosstalk Team
Team Leaders
Faculty Investigators
Indiana University Members - Other Schools

Rafael Bahamonde, PhD
Founding Dean; School of Health & Human Sciences
Purdue University Members

Chad Carroll, PhD
Assistant Professor of Exercise Physiology

Shihuan Kuang, PhD
Professor of Animal Sciences

Tim Gavin, PhD
Chair and Professor of Exercise Physiology

Russell Main, PhD
Associate Professor, Basic Medical Sciences