62070-Mustafa, Hiba

Hiba Mustafa, MD

Assistant Professor of Clinical Obstetrics & Gynecology

UH 2440
Indianapolis, IN


I am a maternal-fetal medicine subspecialist with expertise in the area of fetal diagnosis and therapy. I see patients primarily at the Fetal Center at Riley children’s Health. I take care of high-risk pregnancies, including maternal and
fetal conditions. Within my subspecialty, I have a wide range of training, research, and expertise in fetal diagnosis, fetal intervention, and diagnosis and management of abnormal placentation.

My approach to care for my pregnant patients is thorough assessment including the innovative use of ultrasound approaches like first trimester ultrasound, fetal echocardiography, fetal neurosonography, and 3D/4D imaging for abnormal fetal and placental conditions. I always aspire to provide and create the best care options either through my extensive training by leading experts in the field or through innovative bench-to-bedside research with focus on fetal intervention and surgery for complicated monochorionic twin pregnancies, spina bifida, congenital diaphragmatic hernia, lower urinary tract anomalies and other fetal structural anomalies.

I consider my happiest moments at work are when I scan, operate, conduct research, and teach my medical students, residents, and fellows.

However, my happiest place and times remain at home surrounded by my loving husband and biggest supporter “Hayder” and my three wonderful children “Zain, Adam, and Leah”. Hayder is an Internal-Medicine physician at
Indiana University, he was my medical school sweetheart and together we have had the most rewarding journey. We love to spend most of our free time doing outdoor activities, such as biking, walking, and swimming, and we
tremendously enjoy traveling to new places and explore their history, culture, architecture, and food.

Key Publications

• Single fetal demise following fetoscopic ablation for twin-to-twin transfusion syndrome-cohort study, systematic review, and meta-analysis. Mustafa HJ, Javinani A, Goetzinger K, Aghajani F, Harman C, Shamshirsaz AA, Sanz Cortes M, Donepudi RV, Krispin E, Nassr AA, Espinoza J, Belfort MA, Turan OM.
• Perinatal outcomes of fetoscopic laser surgery for twin-to-twin transfusion syndrome in triplet pregnancies: cohort study, systematic review and meta-analysis H. J. Mustafa, A. Javinani, E. Krispin, H. Tadbiri, A. A. Shamshirsaz, J. Espinoza, A. A. Nassr, R. Donepudi, M. A. Belfort, M. Sanz Cortes, C. Harman, O. M. Turan
• Proximate Cord Insertion in Twin-to-Twin Transfusion Syndrome: Case Series and PRISMA compliant Systematic Review and Meta-analysis. Mustafa HJ, Tadbiri H, Pedersen N, Harman C, Turan OM.
• Efficacy of long-term indomethacin therapy in prolonging pregnancy after fetoscopic laser surgery for twin-to-twin transfusion syndrome: a collaborative cohort study HJ Mustafa, E Krispin, H Tadbiri, J Espinoza, AA Shamshirsaz, AA Nassr, R Donepudi, MA Belfort, MS Cortes, N Pederson, C Harman, OM Turan
• Spontaneous preterm birth and PPROM After Fetoscopic laser Surgery for TTTS- Systematic review and Meta-analysis Hiba J. Mustafa1, MD; Katherine Goetzinger1, MD; Ali Janivani2, MD; Faezeh Aghajani, MD; Christopher Harman1, MD; Alireza A. Shamshirsaz2, MD; Magdalena Sanz Cortes2, MD; Roopali V. Donepudi2, MD; Eyal Krispin2, MD; Ahmed Nassr2, MD; Jimmy Espinoza2, MD; Michael A. Blefort2, MD; Ozhan M. Turan1, MD
• Cerebral Injury in Neonates of Pregnancies Complicated with Twin-to-Twin transfusion syndrome Treated with Laser Ablation Hiba J. Mustafa1, MD; Christopher Harman1, MD; Nicole Pedersen1, BSN; Ozhan M. Turan1, MD
• Post-Laser Ductus Venosus Systolic to Diastolic Ration Predicts Recipient Demise Hiba J. Mustafa1, MD; Hooman Tadbiri1, MD; Christopher Harman1, MD; Sifa Turan1, MD; Nicole Pedersen1, BSN; Ozhan M. Turan1, MD
• Placental Characteristics in Fetuses with Fetal Growth Restriction Undergoing Laser Ablation for Twin-to-Twin Transfusion Syndrome Hiba J. Mustafa1, MD; Christopher Harman1, MD; Nicole Pedersen1, BSN; Ozhan M. Turan1, MD
• Atypical Stage III Twin-to-Twin Transfusion Syndrome, Characteristics and Outcomes Hiba J. Mustafa1, MD; Christopher Harman1, MD; Nicole Pedersen1, BSN; Ozhan M. Turan1, MD
• Perinatal outcomes in Spontaneous and Post Laser Twin Anemia Polycythemia Using Traditional and Delphi Criteria Mustafa, Hiba J. et al. American Journal of Obstetrics & Gynecology, Volume 226, Issue 1, S651
• Iatrogenic chorioamniotic separation and septostomy following fetoscopic laser photocoagulation for twin–twin transfusion syndrome E. Krispin, H. J. Mustafa, R. C. Sun, R. Donepudi, J. Espinoza, A. A. Nassr, M. A. Belfort, M. Sanz Cortes, S. Mostafaei, C. Harman, O. Turan, A. A. Shamshirsaz
• Twin twin transfusion syndrome with and without selective fetal growth restriction: Predictors of donor demise. Donepudi R, Krispin E, Mustafa H, Espinoza J, Nassr AA, Belfort MA, Sanz Cortes M, Mostafaei S, Harman C, Turan O, Shamshirsaz AA.
• Impact of Middle cerebral Artery Pulsatility Index on Donor Survival in Twin-Twin Transfusion Syndrome. American Journal of Obstetrics & GynecologyVol. 226Issue 1SupplementS134–S135Published in issue: January, 2022 Eyal Krispin; Alireza A. Shamshirsaz, Hiba J. Mustafa, Raphael C. Sun, Jimmy Espinoza, Ahmed A. Nassr, and others
• Intertwin differences of cerebroplacental ratio are associated with increased neonatal survival in TTTS; American Journal of Obstetrics & GynecologyVol. 226Issue 1SupplementS332–S333Published in issue: January, 2022 Raphael C. Sun; Lauren Taylor; Rebecca Johnson; Yamely MendezMartinez; Eyal Krispin; Alireza A. Shamshirsaz ; Magdalena Sanz Cortes; Roopali V. Donepudi; Ahmed A. Nassr; Hendrick Lombaard; Michael A. Belfort; Andy Espinoza; Mustafa Hiba; Ozhan M. Turan; Christopher Harman, immy Espinoza
• Chromosomal microarray analysis in the investigation of prenatally diagnosed congenital heart disease. Mustafa HJ, Jacobs KM, Tessier KM, Narasimhan SL, Tofte AN, McCarter AR, Cross SN.
• Predicting dual survival for twin-twin transfusion syndrome following fetoscopic laser photocoagulation; American Journal of Obstetrics & GynecologyVol. 226Issue 1SupplementS470–S471Published in issue: January, 2022 Eyal Krispin; Ahmed A. Nassr; Roopali V. Donepudi; Magdalena Sanz Cortes; Jimmy Espinoza; Hiba J. Mustafa; and others
• Preterm Birth of Infants Prenatally Diagnosed with Congenital Heart Disease, Characteristics, Associations, and Outcomes. Mustafa HJ, Cross SN, Jacobs KM, Tessier KM, Tofte AN, McCarter AR, Narasimhan SL.
• Cytomegalovirus infection elicits a conserved chemokine response from human and guinea pig amnion cells. Putri DS, Berkebile ZW, Mustafa HJ, Fernández-Alarcón C, Abrahante JE, Schleiss MR, Bierle CJ.
• Fetal growth standards for Somali population. Mustafa HJ, Tessier KM, Reagan LA, Luo X, Contag SA.
• Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy. Lahrouchi N, Postma AV, Salazar CM, De Laughter DM, Tjong F, Piherová L, Bowling FZ, Zimmerman D, Lodder EM, Ta-Shma A, Perles Z, Beekman L, Ilgun A, Gunst Q, Hababa M, Škoric-Milosavljevic D, Stránecký V, Tomek V, de Knijff P, de Leeuw R, Robinson JY, Burn SC, Mustafa H, Ambrose M, Moss T, Jacober J, Niyazov DM, Wolf B, Kim KH, Cherny S, Rousounides A, Aristidou-Kallika A, Tanteles G, Ange-Line B, Denommé-Pichon AS, Francannet C, Ortiz D, Haak MC, Ten Harkel AD, Manten GT, Dutman AC, Bouman K, Magliozzi M, Radio FC, Santen GW, Herkert JC, Brown HA, Elpeleg O, van den Hoff MJ, Mulder B, Airola MV, Kmoch S, Barnett JV, Clur SA, Frohman MA, Bezzina CR.

Titles & Appointments

  • Assistant Professor of Clinical Obstetrics & Gynecology
  • Education
    2022 FEL Fetal Surgery Fellowship, University of Maryland
    2020 FEL Maternal-Fetal Medicine Fellowship, University of Minnesota
    2017 RES Obstetrics and Gynecology Residency, Icahn School of Medicine at Mount Sinai
    2008 MD University of Baghdad
  • Research
    • Fetal surgery for complicated monochorionic pregnancies including twin-to-twin transfusion syndrome, twin-anemia polycythemia sequence, selective fetal growth restriction, twin reversed arterial perfusion sequence.
    • In-utero repair of spina bifida
    • Congenital diaphragmatic hernia
    • Diagnosis and in-utero therapy for fetal lower urinary tract obstruction
    • Diagnosis and in-utero therapy for Fetal anemia, Thrombocytopenia, and Hemoglobinopathy
    • Diagnosis and in-utero therapy for fetal pleural effusion
    • Resection of fetal amniotic band sequence
    • EXIT Procedure
    • Fetoscopic and ultrasound-guided procedures for fetal tumors such as teratoma and placental tumors such as chorioangioma
    • Diagnostic genetic testing including abdominal and transcervical chorionic villous sampling (CVS), and amniocentesis
    • Diagnosis and Ultrasound-guided management of cesarean scar pregnancy
    • Diagnosis and management of abnormal placentation such as placenta accrete spectrum
    • Imaging including first trimester ultrasound and echocardiography, fetal neurosonography, 3D/4D
    ultrasound, and ultrasound in pregnancies with severe obesity
    • Vaginal and abdominal cerclage placement
  • Board Certifications
    American Board of Obstetrics and Gynecology - Maternal and Fetal Medicine
    American Board of Obstetrics and Gynecology - Obstetrics and Gynecology
  • Clinical Interests
    Fetoscopic fetal surgery, fetal shunt placement, fetal transfusion, EXIT procedure, cervical and abdominal CVS, cervical and abdominal cerclage, placenta accrete diagnosis and surgery, fetal brain anomalies and neurosonography, and cesarean scar diagnosis and management

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