Key Publications
Liu, Y., Wang, T., Duggan, B., Huang, K., Zhang, J., Ye, X., Johnson, T.S. (2022). SPCS: A Spatial and Pattern Combined Smoothing Method for Spatial Transcriptomics Expression. Briefings in Bioinformatics.
Sharpnack, M. F.*, Johnson, T. S.*, Chalkley, R., Han, Z., Carbone, D., Huang, K., He, K. (2022). TSAFinder: Exhaustive Tumor Specific Antigen Detection with RNAseq. Bioinformatics.
Johnson, T. S., Christina, Y. Y., Huang, Z., Xu, S., Wang, T., Dong, C., ... & Zhang, Y. (2022). Diagnostic Evidence GAuge of Single cells (DEGAS): A flexible deep-transfer learning framework for prioritizing cells in relation to disease. Genome Medicine,14(1), 1-23.
Huang, X., Huang, K., Johnson, T., Radovich, M., Zhang, J., Ma, J., & Wang, Y. (2021). ParsVNN: parsimony visible neural networks for uncovering cancer-specific and drug-sensitive genes and pathways. NAR Genomics and Bioinformatics, 3(4), lqab097.
Xu, C., Sun, S., Johnson, T., Qi, R., Zhang, S., Zhang, J., & Yang, K. (2021). The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity. Cell Reports, 35(11), 109235.
Wang, T., Johnson, T. S., Shao, W., Lu, Z., Helm, B. R., Zhang, J., & Huang, K. (2019). BERMUDA: a novel deep transfer learning method for single-cell RNA sequencing batch correction reveals hidden high-resolution cellular subtypes. Genome Biology, 20(1), 1-15.Sharpnack, M. F.*, Johnson, T. S.*, Chalkley, R., Han, Z., Carbone, D., Huang, K., He, K. (2022). TSAFinder: Exhaustive Tumor Specific Antigen Detection with RNAseq. Bioinformatics.
Johnson, T. S., Christina, Y. Y., Huang, Z., Xu, S., Wang, T., Dong, C., ... & Zhang, Y. (2022). Diagnostic Evidence GAuge of Single cells (DEGAS): A flexible deep-transfer learning framework for prioritizing cells in relation to disease. Genome Medicine,14(1), 1-23.
Huang, X., Huang, K., Johnson, T., Radovich, M., Zhang, J., Ma, J., & Wang, Y. (2021). ParsVNN: parsimony visible neural networks for uncovering cancer-specific and drug-sensitive genes and pathways. NAR Genomics and Bioinformatics, 3(4), lqab097.
Xu, C., Sun, S., Johnson, T., Qi, R., Zhang, S., Zhang, J., & Yang, K. (2021). The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity. Cell Reports, 35(11), 109235.
Johnson, T.S., Wang, T., Huang, Z., Yu, C.Y., Wu, Y., Han, Y., Zhang, Y., Huang, K., Zhang, J. (2019). LAmbDA: Label Ambiguous Domain Adaptation Dataset Integration Reduces Batch Effects and Improves Subtype Detection. Bioinformatics, 35(22), 4696-4706.
Johnson, T.S., Li, S., Franz, E., Huang, Z., Li, S.D., Campbell, M.J., Huang, K., Zhang, Y. (2019). PseudoFuN: Deriving functional potentials of pseudogenes from integrative relationships with genes and microRNAs across 32 cancers. Gigascience, 8(5), giz046.
Titles & Appointments
- Agnes Beaudry Investigator in Myeloma Research
- Assistant Professor of Biostatistics & Health Data Science
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Education
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Research
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Professional Organizations
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Awards
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