Faculty

Patrick J. Loehrer, MD

Distinguished Professor

Email ploehrer@iu.edu

Phone (317) 948-1186

Address

Indiana Cancer Pavilion, Room 455
535 Barnhill Dr.

Indianapolis , IN 46202-5289

Bio

Principal Investigator or Co-Principal Investigator in numerous currently active recently completed clinical protocols. These studies include not only university studies but also multi-institutional (ECOG and SECSG)and international intergroup studies.

Treatments in thymoma, GU (e.g. bladder cancer, testis cancer), GI cancer (e.g. pancreatic cancer, colon cancer, cancer).

Titles & Appointments

Distinguished Professor
Joseph W. and Jackie J. Cusick Professor of Oncology
Professor of Medicine
Program Leader - Global Oncology

Education

1983 FEL Fellowship, Indiana University Medical Center, Indianapolis, IN

1981 RES Residency, Rush-Presbyterian St. Luke's Medical Center, Chicago, IL

1978 MD Rush University

1975 BS Purdue University
Research

Principal Investigator or Co-Principal Investigator in numerous currently active recently completed clinical protocols. These studies include not only university studies but also multi-institutional (ECOG and SECSG)and international intergroup studies.
Publications

Adjuvant Gemcitabine and Gemcitabine-based Chemoradiotherapy Versus Gemcitabine Alone After Pancreatic Cancer Resection: The Indiana University Experience.
Khawaja MR; Kleyman S; Yu Z; Howard T; Burns M; Nakeeb A; Loehrer PJ Sr; Cardenes HR; Chiorean EG; American journal of clinical oncology 2017 Feb

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.
Dittrich C; Kosty M; Jezdic S; Pyle D; Berardi R; Bergh J; El-Saghir N; Lotz JP; Österlund P; Pavlidis N; Purkalne G; Awada A; Banerjee S; Bhatia S; Bogaerts J; Buckner J; Cardoso F; Casali P; Chu E; Close JL; Coiffier B; Connolly R; Coupland S; De Petris L; De Santis M; de Vries EG; Dizon DS; Duff J; Duska LR; Eniu A; Ernstoff M; Felip E; Fey MF; Gilbert J; Girard N; Glaudemans AW; Gopalan PK; Grothey A; Hahn SM; Hanna D; Herold C; Herrstedt J; Homicsko K; Jones DV Jr; Jost L; Keilholz U; Khan S; Kiss A; Köhne CH; Kunstfeld R; Lenz HJ; Lichtman S; Licitra L; Lion T; Litière S; Liu L; Loehrer PJ; Markham MJ; Markman B; Mayerhoefer M; Meran JG; Michielin O; Moser EC; Mountzios G; Moynihan T; Nielsen T; Ohe Y; Öberg K; Palumbo A; Peccatori FA; Pfeilstöcker M; Raut C; Remick SC; Robson M; Rutkowski P; Salgado R; Schapira L; Schernhammer E; Schlumberger M; Schmoll HJ; Schnipper L; Sessa C; Shapiro CL; Steele J; Sternberg CN; Stiefel F; Strasser F; Stupp R; Sullivan R; Tabernero J; Travado L; Verheij M; Voest E; Vokes E; Von Roenn J; Weber JS; Wildiers H; Yarden Y; ESMO open 2016 Sep 29

Phase I Study of Lenalidomide and Sorafenib in Patients With Advanced Hepatocellular Carcinoma.
Shahda S; Loehrer PJ; Clark RS; Spittler AJ; Althouse SK; Chiorean EG; The oncologist 2016 Jun 2

A large microRNA cluster on chromosome 19 is a transcriptional hallmark of WHO type A and AB thymomas.
Radovich M; Solzak JP; Hancock BA; Conces ML; Atale R; Porter RF; Zhu J; Glasscock J; Kesler KA; Badve SS; Schneider BP; Loehrer PJ; British journal of cancer 2016 Jan 14

Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers.
Radovich M; Kiel PJ; Nance SM; Niland EE; Parsley ME; Ferguson ME; Jiang G; Ammakkanavar NR; Einhorn LH; Cheng L; Nassiri M; Davidson DD; Rushing DA; Loehrer PJ; Pili R; Hanna N; Callaghan JT; Skaar TC; Helft PR; Shahda S; O'Neil BH; Schneider BP; Oncotarget 2016 Aug 30

Integration of Palliative Care Into Comprehensive Cancer Treatment at Moi Teaching and Referral Hospital in Western Kenya.
Cornetta K; Kipsang S; Gramelspacher G; Choi E; Brown C; Hill AB; Loehrer PJ; Busakhala N; Chite Asirwa F; Journal of global oncology 2015 Sep 23

Micronodular thymic neoplasms: case series and literature review with emphasis on the spectrum of differentiation.
Mneimneh WS; Gökmen-Polar Y; Kesler KA; Loehrer PJ Sr; Badve S; Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2015 Sep 11

Are There Differences in Treatment and Survival Between Poor, Older Black and White Women with Breast Cancer?
Aggarwal H; Callahan CM; Miller KD; Tu W; Loehrer PJ Sr; Journal of the American Geriatrics Society 2015 Oct 12

Medical Education and Training: Building In-Country Capacity at All Levels.
Chite Asirwa F; Greist A; Busakhala N; Rosen B; Loehrer PJ Sr; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015 Nov 17

Exploring Metabolic Profile Differences between Colorectal Polyp Patients and Controls Using Seemingly Unrelated Regression.
Chen C; Deng L; Wei S; Nagana Gowda GA; Gu H; Chiorean EG; Abu Zaid M; Harrison ML; Pekny JF; Loehrer PJ; Zhang D; Zhang M; Raftery D; Journal of proteome research 2015 May 13

Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial.
Thomas A; Rajan A; Berman A; Tomita Y; Brzezniak C; Lee MJ; Lee S; Ling A; Spittler AJ; Carter CA; Guha U; Wang Y; Szabo E; Meltzer P; Steinberg SM; Trepel JB; Loehrer PJ; Giaccone G; The Lancet. Oncology 2015 Jan 13

A phase II study of saracatinib (AZD0530), a Src inhibitor, administered orally daily to patients with advanced thymic malignancies.
Gubens MA; Burns M; Perkins SM; Pedro-Salcedo MS; Althouse SK; Loehrer PJ; Wakelee HA; Lung cancer (Amsterdam, Netherlands) 2015 Apr 25

Critical role of NF-?B in pancreatic cancer.
Prabhu L; Mundade R; Korc M; Loehrer PJ; Lu T; Oncotarget 2014 Nov 30

NUT midline carcinomas in the thymic region.
Gökmen-Polar Y; Cano OD; Kesler KA; Loehrer PJ; Badve S; Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2014 May 23

Contribution of environment and genetics to pancreatic cancer susceptibility.
Hocevar BA; Kamendulis LM; Pu X; Perkins SM; Wang ZY; Johnston EL; DeWitt JM; Li L; Loehrer PJ; Klaunig JE; Chiorean EG; PloS one 2014 Mar 20

Genetic pathways, prevention, and treatment of sporadic colorectal cancer.
Mundade R; Imperiale TF; Prabhu L; Loehrer PJ; Lu T; Oncoscience 2014 Jun 30

[Standard outcome measures for thymic malignancies].
Huang J; Detterbeck FC; Wang Z; Loehrer PJ; Zhongguo fei ai za zhi = Chinese journal of lung cancer 2014 Feb

[Chemotherapy definitions and policies for thymic malignancies].
Girard N; Lal R; Wakelee H; Riely GJ; Loehrer PJ; International Thymic Malignancy Interest Group.; Zhongguo fei ai za zhi = Chinese journal of lung cancer 2014 Feb

NUT Midline Carcinoma Masquerading As a Thymic Carcinoma.
Gökmen-Polar Y; Kesler K; Loehrer PJ Sr; Badve S; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2014 Apr 14

Phase 1 pharmacogenetic and pharmacodynamic study of sorafenib with concurrent radiation therapy and gemcitabine in locally advanced unresectable pancreatic cancer.
Chiorean EG; Schneider BP; Akisik FM; Perkins SM; Anderson S; Johnson CS; DeWitt J; Helft P; Clark R; Johnston EL; Spittler AJ; Deluca J; Bu G; Shahda S; Loehrer PJ; Sandrasegaran K; Cardenes HR; International journal of radiation oncology, biology, physics 2014 Apr 11

The National Cancer Institute-American Society of Clinical Oncology Cancer Trial Accrual Symposium: summary and recommendations.
Denicoff AM; McCaskill-Stevens W; Grubbs SS; Bruinooge SS; Comis RL; Devine P; Dilts DM; Duff ME; Ford JG; Joffe S; Schapira L; Weinfurt KP; Michaels M; Raghavan D; Richmond ES; Zon R; Albrecht TL; Bookman MA; Dowlati A; Enos RA; Fouad MN; Good M; Hicks WJ; Loehrer PJ Sr; Lyss AP; Wolff SN; Wujcik DM; Meropol NJ; Journal of oncology practice 2013 Oct 15

The prognostic value of architectural patterns in a study of 37 type AB thymomas.
Vladislav IT; Gökmen-Polar Y; Kesler KA; Loehrer PJ Sr; Badve S; Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Nov 15

Opportunistic infections in a patient with HIV and thymoma.
Leathers CA; Azar MM; Badve SS; Roth TD; Loehrer PJ; Nelson RP Jr; The journal of allergy and clinical immunology. In practice 2013 May 27

A gene signature to determine metastatic behavior in thymomas.
Gökmen-Polar Y; Cook RW; Goswami CP; Wilkinson J; Maetzold D; Stone JF; Oelschlager KM; Vladislav IT; Shirar KL; Kesler KA; Loehrer PJ Sr; Badve S; PloS one 2013 Jul 24

Elevated phospholipase A2 activities in plasma samples from multiple cancers.
Cai H; Chiorean EG; Chiorean MV; Rex DK; Robb BW; Hahn NM; Liu Z; Loehrer PJ; Harrison ML; Xu Y; PloS one 2013 Feb 22

Qualitative analysis of practicing oncologists' attitudes and experiences regarding collection of patient-reported outcomes.
Jagsi R; Chiang A; Polite BN; Medeiros BC; McNiff K; Abernethy AP; Zon R; Loehrer PJ Sr; Journal of oncology practice 2013 Aug 6

The role of histology in predicting recurrence of type A thymomas: a clinicopathologic correlation of 23 cases.
Vladislav IT; Gökmen-Polar Y; Kesler KA; Loehrer PJ Sr; Badve S; Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Apr 12

Building cancer nursing skills in a resource-constrained government hospital.
Strother RM; Fitch M; Kamau P; Beattie K; Boudreau A; Busakhalla N; Loehrer PJ; Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2012 May 8

Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53.
Chiorean EG; Sanghani S; Schiel MA; Yu M; Burns M; Tong Y; Hinkle DT; Coleman N; Robb B; LeBlanc J; Clark R; Bufill J; Curie C; Loehrer PJ; Cardenes H; Cancer chemotherapy and pharmacology 2012 May 18

Thymic carcinoma: outcomes after surgical resection.
Okereke IC; Kesler KA; Freeman RK; Rieger KM; Birdas TJ; Ascioti AJ; Badve S; Nelson RP; Loehrer PJ; The Annals of thoracic surgery 2012 Mar 14

Immune-mediated diseases and immunodeficiencies associated with thymic epithelial neoplasms.
Khawaja MR; Nelson RP Jr; Miller N; Badve SS; Loehrer E; Czader M; Perkins SM; Kesler K; Loehrer PJ Sr; Journal of clinical immunology 2012 Jan 8

The oncology pharmacy in cancer care delivery in a resource-constrained setting in western Kenya.
Strother RM; Rao KV; Gregory KM; Jakait B; Busakhala N; Schellhase E; Pastakia S; Krzyzanowska M; Loehrer PJ; Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 2012 Jan 16

Establishment and characterization of a novel cell line derived from human thymoma AB tumor.
Gökmen-Polar Y; Sanders KL; Goswami CP; Cano OD; Zaheer NA; Jain RK; Kesler KA; Nelson RP Jr; Vance GH; Smith D; Li L; Cardoso AA; Badve S; Loehrer PJ Sr; Sledge GW Jr; Laboratory investigation; a journal of technical methods and pathology 2012 Aug 27

Molecular analysis of thymoma.
Badve S; Goswami C; Gökmen-Polar Y; Nelson RP Jr; Henley J; Miller N; Zaheer NA; Sledge GW Jr; Li L; Kesler KA; Loehrer PJ Sr; PloS one 2012 Aug 13

Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial.
Loehrer PJ Sr; Feng Y; Cardenes H; Wagner L; Brell JM; Cella D; Flynn P; Ramanathan RK; Crane CH; Alberts SR; Benson AB 3rd; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Oct 3

A phase II study of gemcitabine in combination with radiation therapy in patients with localized, unresectable, pancreatic cancer: a Hoosier Oncology Group study.
Cardenes HR; Moore AM; Johnson CS; Yu M; Helft P; Chiorean EG; Vinson J; Howard TJ; Stephens AW; Tai DF; Loehrer PJ Sr; American journal of clinical oncology 2011 Oct

Extrathoracic metastases of thymic origin: a review of 35 cases.
Vladislav T; Jain RK; Alvarez R; Mehta RJ; Gökmen-Polar Y; Kesler KA; Henley JD; Loehrer PJ Sr; Badve S; Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011 Nov 11

Phase II trial of erlotinib and docetaxel in advanced and refractory hepatocellular and biliary cancers: Hoosier Oncology Group GI06-101.
Chiorean EG; Ramasubbaiah R; Yu M; Picus J; Bufill JA; Tong Y; Coleman N; Johnston EL; Currie C; Loehrer PJ; The oncologist 2011 Dec 30

Phase II study of carboplatin and paclitaxel in advanced thymoma and thymic carcinoma.
Lemma GL; Lee JW; Aisner SC; Langer CJ; Tester WJ; Johnson DH; Loehrer PJ Sr; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011 Apr 18

WHO types A and AB thymomas: not always benign.
Jain RK; Mehta RJ; Henley JD; Kesler KA; Loehrer PJ; Badve S; Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010 Sep 10

The role of chemotherapy in advanced thymoma.
Schmitt J; Loehrer PJ Sr; Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010 Oct

Retrospective analysis of the efficacy of gemcitabine for previously treated AIDS-associated Kaposi's sarcoma in western Kenya.
Strother RM; Gregory KM; Pastakia SD; Were P; Tenge C; Busakhala N; Jakait B; Schellhase EM; Rosmarin AG; Loehrer PJ; Oncology 2010 Mar 6

Prognostic indicators after surgery for thymoma.
Okereke IC; Kesler KA; Morad MH; Mi D; Rieger KM; Birdas TJ; Badve S; Henley JD; Turrentine MW; Nelson RP; Loehrer PJ; The Annals of thoracic surgery 2010 Apr

A phase 2 trial of glufosfamide in combination with gemcitabine in chemotherapy-naive pancreatic adenocarcinoma.
Chiorean EG; Dragovich T; Hamm J; Barrios CH; Gorini CF; Langmuir VK; Kroll S; Jung DT; Tidmarsh GT; Loehrer PJ; American journal of clinical oncology 2010 Apr

Postoperative radiotherapy after surgical resection of thymoma: differing roles in localized and regional disease.
Forquer JA; Rong N; Fakiris AJ; Loehrer PJ Sr; Johnstone PA; International journal of radiation oncology, biology, physics 2009 May 8

Rituximab for the treatment of thymoma-associated and de novo myasthenia gravis: 3 cases and review.
Nelson RP Jr; Pascuzzi RM; Kessler K; Walsh LE; Faught PP; Ramanuja S; Pescovitz MD; Loehrer PJ Sr; Journal of clinical neuromuscular disease 2009 Jun

Clinical management of thymoma patients.
Casey EM; Kiel PJ; Loehrer PJ Sr; Hematology/oncology clinics of North America 2008 Jun

A phase II trial of olanzapine, dexamethasone, and palonosetron for the prevention of chemotherapy-induced nausea and vomiting: a Hoosier oncology group study.
Navari RM; Einhorn LH; Loehrer PJ Sr; Passik SD; Vinson J; McClean J; Chowhan N; Hanna NH; Johnson CS; Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2007 Mar 21

A Phase 1 dose-escalation trial of glufosfamide in combination with gemcitabine in solid tumors including pancreatic adenocarcinoma.
Chiorean EG; Dragovich T; Hamm J; Langmuir VK; Kroll S; Jung DT; Colowick AB; Tidmarsh GF; Loehrer PJ; Cancer chemotherapy and pharmacology 2007 Jul 28

HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation.
Jung C; Kim RS; Zhang H; Lee SJ; Sheng H; Loehrer PJ; Gardner TA; Jeng MH; Kao C; British journal of cancer 2005 Jun 20

Thymoma: current medical and surgical management.
Kesler KA; Wright CD; Loehrer PJ Sr; Seminars in neurology 2004 Mar

Thymoma and thymic carcinoma: therapeutic approaches.
Kurup A; Loehrer PJ Sr; Clinical lung cancer 2004 Jul

Pancreaticoduodenectomy: a 20-year experience in 516 patients.
Schmidt CM; Powell ES; Yiannoutsos CT; Howard TJ; Wiebke EA; Wiesenauer CA; Baumgardner JA; Cummings OW; Jacobson LE; Broadie TA; Canal DF; Goulet RJ Jr; Curie EA; Cardenes H; Watkins JM; Loehrer PJ; Lillemoe KD; Madura JA; Archives of surgery (Chicago, Ill. : 1960) 2004 Jul

Octreotide alone or with prednisone in patients with advanced thymoma and thymic carcinoma: an Eastern Cooperative Oncology Group Phase II Trial.
Loehrer PJ Sr; Wang W; Johnson DH; Aisner SC; Ettinger DS; Eastern Cooperative Oncology Group Phase II Trial.; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004 Jan 15

Tyrosine kinase receptor expression in thymomas.
Henley JD; Cummings OW; Loehrer PJ Sr; Journal of cancer research and clinical oncology 2004 Feb 5

Antitumor effects of 5-fluorouracil on human colon cancer cell lines: antagonism by levamisole.
Wiebke EA; Grieshop NA; Loehrer PJ; Eckert GJ; Sidner RA; The Journal of surgical research 2003 May 1

Cisplatin, etoposide and either bleomycin or ifosfamide in the treatment of disseminated germ cell tumors: final analysis of an intergroup trial.
Hinton S; Catalano PJ; Einhorn LH; Nichols CR; David Crawford E; Vogelzang N; Trump D; Loehrer PJ Sr; Cancer 2003 Apr 15

Phase II study of gemcitabine plus docetaxel in advanced pancreatic cancer: a Hoosier Oncology Group study.
Schneider BP; Ganjoo KN; Seitz DE; Picus J; Fata F; Stoner C; Calley C; Loehrer PJ; Oncology 2003

Epidermal growth factor receptor expression in invasive thymoma.
Henley JD; Koukoulis GK; Loehrer PJ Sr; Journal of cancer research and clinical oncology 2002 Jan 30

Maintenance daily oral etoposide versus no further therapy following induction chemotherapy with etoposide plus ifosfamide plus cisplatin in extensive small-cell lung cancer: a Hoosier Oncology Group randomized study.
Hanna NH; Sandier AB; Loehrer PJ Sr; Ansari R; Jung SH; Lane K; Einhorn LH; Annals of oncology : official journal of the European Society for Medical Oncology 2002 Jan

Phase II study of paclitaxel plus gemcitabine in refractory germ cell tumors (E9897): a trial of the Eastern Cooperative Oncology Group.
Hinton S; Catalano P; Einhorn LH; Loehrer PJ Sr; Kuzel T; Vaughn D; Wilding G; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002 Apr 1

A phase I study of weekly gemcitabine and docetaxel in patients with advanced cancer: a Hoosier Oncology Group Study.
Ganjoo KN; Gordon MS; Sandler AB; Warner RE; Fife K; Poirier S; Seshadri R; Loehrer PJ; Oncology 2002

High-dose carboplatin with etoposide in patients with recurrent thymoma: the Indiana University experience.
Hanna N; Gharpure VS; Abonour R; Cornetta K; Loehrer PJ Sr; Bone marrow transplantation 2001 Sep

Combined etoposide, ifosfamide, and cisplatin in the treatment of patients with advanced thymoma and thymic carcinoma: an intergroup trial.
Loehrer PJ Sr; Jiroutek M; Aisner S; Aisner J; Green M; Thomas CR Jr; Livingston R; Johnson DH; Cancer 2001 Jun 1

Altretamine for the treatment of metastatic renal cell carcinoma. A Hoosier Oncology Group trial.
Zon RT; McClean J; Helman D; Ansari R; Picus J; Sandler A; Williams SD; Loehrer PJ Sr; Investigational new drugs 2001

Thymic malignancies.
Loehrer PJ Sr; Wick MR; Cancer treatment and research 2001

Phase II study of the multitargeted antifolate LY231514 (ALIMTA, MTA, pemetrexed disodium) in patients with advanced pancreatic cancer.
Miller KD; Picus J; Blanke C; John W; Clark J; Shulman LN; Thornton D; Rowinsky E; Loehrer PJ Sr; Annals of oncology : official journal of the European Society for Medical Oncology 2000 Jan

Lung cancer presenting with solitary bone metastases. Case 1: metastatic adenocarcinoma to the patella.
Ganjoo KN; Loyal JA; Cramer HM; Loehrer PJ; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999 Sep

Sacrococcygeal teratoma in adults: case reports and a review of the literature.
Ng EW; Porcu P; Loehrer PJ Sr; Cancer 1999 Oct 1

Current approaches to the treatment of thymoma.
Loehrer PJ Sr; Annals of medicine 1999 Oct

Vinblastine plus ifosfamide plus cisplatin as initial salvage therapy in recurrent germ cell tumor.
Loehrer PJ Sr; Gonin R; Nichols CR; Weathers T; Einhorn LH; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 Jul

Prospective randomized trial of 5-fluorouracil versus 5-fluorouracil plus levamisole in the treatment of metastatic colorectal cancer: a Hoosier Oncology Group trial.
Bandealy MT; Gonin R; Loehrer PJ; Monaco F; Einhorn LH; Clinical cancer research : an official journal of the American Association for Cancer Research 1998 Apr

Randomized comparison of cisplatin and etoposide and either bleomycin or ifosfamide in treatment of advanced disseminated germ cell tumors: an Eastern Cooperative Oncology Group, Southwest Oncology Group, and Cancer and Leukemia Group B Study.
Nichols CR; Catalano PJ; Crawford ED; Vogelzang NJ; Einhorn LH; Loehrer PJ; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998 Apr

Paclitaxel plus gallium nitrate and filgrastim in patients with refractory malignancies: a phase I trial.
Sandler A; Fox S; Meyers T; Christou A; Weber G; Gonin R; Loehrer PJ; Einhorn LH; Dreicer R; American journal of clinical oncology 1998 Apr

Cisplatin, doxorubicin, and cyclophosphamide plus thoracic radiation therapy for limited-stage unresectable thymoma: an intergroup trial.
Loehrer PJ Sr; Chen M; Kim K; Aisner SC; Einhorn LH; Livingston R; Johnson D; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997 Sep

Long-term follow-up of a phase III intergroup study of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study.
Saxman SB; Propert KJ; Einhorn LH; Crawford ED; Tannock I; Raghavan D; Loehrer PJ Sr; Trump D; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997 Jul

Salvage chemotherapy with vinblastine, ifosfamide, and cisplatin in recurrent seminoma.
Miller KD; Loehrer PJ; Gonin R; Einhorn LH; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997 Apr

Thymic neoplasms.
Debono DJ; Loehrer PJ; Current opinion in oncology 1996 Mar

The role of ifosfamide in small cell lung cancer.
Loehrer PJ Sr; Seminars in oncology 1996 Jun

A phase II study of weekly oral methotrexate and zidovudine (AZT) in advanced adenocarcinoma of the pancreas and hepatocellular carcinoma.
Miller KD; Loehrer PJ; Gonin R; Weber G; Ansari R; Pletcher W; McClean J; Spiridonidis CH; Mortimer J; Investigational new drugs 1996

Biology of metastases and its clinical implications: testicular germ-cell tumors.
Donohue JP; Foster RS; Little JS Jr; Loehrer PJ; Einhorn LE; World journal of urology 1996

A phase II trial of subcutaneously administered recombinant human interleukin-2 in patients with relapsed/refractory thymoma.
Gordon MS; Battiato LA; Gonin R; Harrison-Mann BC; Loehrer PJ Sr; Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1995 Oct

Cisplatin plus etoposide with and without ifosfamide in extensive small-cell lung cancer: a Hoosier Oncology Group study.
Loehrer PJ Sr; Ansari R; Gonin R; Monaco F; Fisher W; Sandler A; Einhorn LH; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995 Oct

Importance of bleomycin in favorable-prognosis disseminated germ cell tumors: an Eastern Cooperative Oncology Group trial.
Loehrer PJ Sr; Johnson D; Elson P; Einhorn LH; Trump D; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995 Feb

Palliative therapy: extensive small cell lung cancer.
Loehrer PJ Sr; Seminars in oncology 1995 Apr

Salvage chemotherapy for recurrent germ cell cancer.
Nichols CR; Roth BJ; Loehrer PJ; Williams SD; Einhorn LH; Seminars in oncology 1994 Oct

Phase II trial of vinblastine, ifosfamide, and gallium combination chemotherapy in metastatic urothelial carcinoma.
Einhorn LH; Roth BJ; Ansari R; Dreicer R; Gonin R; Loehrer PJ; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994 Nov

Significant activity of paclitaxel in advanced transitional-cell carcinoma of the urothelium: a phase II trial of the Eastern Cooperative Oncology Group.
Roth BJ; Dreicer R; Einhorn LH; Neuberg D; Johnson DH; Smith JL; Hudes GR; Schultz SM; Loehrer PJ; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994 Nov

Early salvage therapy for germ cell cancer using high dose chemotherapy with autologous bone marrow support.
Broun ER; Nichols CR; Turns M; Williams SD; Loehrer PJ; Roth BJ; Lazarus HM; Einhorn LH; Cancer 1994 Mar 15

Escalated dosages of methotrexate, vinblastine, doxorubicin, and cisplatin plus recombinant human granulocyte colony-stimulating factor in advanced urothelial carcinoma: an Eastern Cooperative Oncology Group trial.
Loehrer PJ Sr; Elson P; Dreicer R; Hahn R; Nichols CR; Williams R; Einhorn LH; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994 Mar

Cisplatin plus doxorubicin plus cyclophosphamide in metastatic or recurrent thymoma: final results of an intergroup trial. The Eastern Cooperative Oncology Group, Southwest Oncology Group, and Southeastern Cancer Study Group.
Loehrer PJ Sr; Kim K; Aisner SC; Livingston R; Einhorn LH; Johnson D; Blum R; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994 Jun

Incidence of neutropenic fever in patients treated with standard-dose combination chemotherapy for small-cell lung cancer and the cost impact of treatment with granulocyte colony-stimulating factor.
Nichols CR; Fox EP; Roth BJ; Williams SD; Loehrer PJ; Einhorn LH; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994 Jun

A phase II trial of vinblastine plus dipyridamole in advanced renal cell carcinoma. A Hoosier Oncology Group Study.
Murphy BR; Rynard SM; Pennington KL; Grosh W; Loehrer PJ; American journal of clinical oncology 1994 Feb

5-fluorouracil vs. epirubicin vs. 5-fluorouracil plus epirubicin in advanced gastric carcinoma.
Loehrer PJ Sr; Harry D; Chlebowski RT; Investigational new drugs 1994

Synergism of taxol and gallium nitrate in human breast carcinoma cells: schedule dependency.
Hata Y; Sandler A; Loehrer PJ; Sledge GW Jr; Weber G; Oncology research 1994

Persistent cancer in postchemotherapy retroperitoneal lymph-node dissection: outcome analysis.
Donohue JP; Fox EP; Williams SD; Loehrer PJ; Ulbright TM; Einhorn LH; Weathers TD; World journal of urology 1994

Taxol in advanced, hormone-refractory carcinoma of the prostate. A phase II trial of the Eastern Cooperative Oncology Group.
Roth BJ; Yeap BY; Wilding G; Kasimis B; McLeod D; Loehrer PJ; Cancer 1993 Oct 15

Outcome analysis for patients with persistent nonteratomatous germ cell tumor in postchemotherapy retroperitoneal lymph node dissections.
Fox EP; Weathers TD; Williams SD; Loehrer PJ; Ulbright TM; Donohue JP; Einhorn LH; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993 Jul

Secondary leukemia associated with a conventional dose of etoposide: review of serial germ cell tumor protocols.
Nichols CR; Breeden ES; Loehrer PJ; Williams SD; Einhorn LH; Journal of the National Cancer Institute 1993 Jan 6

Thymic carcinoma. A distinct clinical entity responsive to chemotherapy.
Weide LG; Ulbright TM; Loehrer PJ Sr; Williams SD; Cancer 1993 Feb 15

Colonic adenomas in asymptomatic women with a history of breast cancer.
Rex DK; Sledge GW; Harper PA; Ulbright TM; Loehrer PJ; Helper DJ; Smith JJ; Wiersema MJ; Hawes RH; Lehman GA; The American journal of gastroenterology 1993 Dec

Thymomas. Current experience and future directions in therapy.
Loehrer PJ; Drugs 1993 Apr

Knowledge in cancer beliefs: obstacles to care?
Loehrer PJ Sr; Cancer treatment reviews 1993

Dose intensity in germ cell cancer: continued lessons from a model neoplasm.
Nichols CR; Roth BJ; Broun ER; Loehrer PJ; Williams SD; Einhorn LH; European urology 1993

Testicular ultrasonography after chemotherapy for germ cell neoplasm: significance of highly hyperechoic lesions.
Kopecky KK; Brendle MT; Harman JT; Foster RS; Bihrle R; Loehrer PJ; Urology 1992 May

Long-term outcome of patients with relapsed and refractory germ cell tumors treated with high-dose chemotherapy and autologous bone marrow rescue.
Broun ER; Nichols CR; Kneebone P; Williams SD; Loehrer PJ; Einhorn LH; Tricot GJ; Annals of internal medicine 1992 Jul 15

A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study.
Loehrer PJ Sr; Einhorn LH; Elson PJ; Crawford ED; Kuebler P; Tannock I; Raghavan D; Stuart-Harris R; Sarosdy MF; Lowe BA; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992 Jul

Etoposide, ifosfamide, and cisplatin in extensive small cell lung cancer.
Loehrer PJ Sr; Rynard S; Ansari R; Songer J; Pennington K; Einhorn L; Cancer 1992 Feb 1

Clinical trials with ifosfamide: the Indiana University experience.
Loehrer PJ; Williams SD; Nichols CR; Einhorn LH; Seminars in oncology 1992 Feb

The history of ifosfamide.
Loehrer PJ Sr; Seminars in oncology 1992 Dec

Chronic oral etoposide: trials at Indiana University and with the Hoosier Oncology Group.
Loehrer PJ Sr; Seminars in oncology 1992 Dec

Chemoradiotherapy in locally advanced bladder carcinoma.
Loehrer PJ Sr; Seminars in oncology 1992 Aug

Comparison of N-acetylcysteine and mesna as uroprotectors with ifosfamide combination chemotherapy in refractory germ cell tumors.
Munshi NC; Loehrer PJ Sr; Williams SD; Langefeld C; Sledge G; Nichols CR; Roth BJ; Neuman A; Walsh WB; Einhorn LH; Investigational new drugs 1992 Aug

A phase II trial of interferon alpha-2A plus fluorouracil in advanced renal cell carcinoma. A Hoosier Oncology Group study.
Murphy BR; Rynard SM; Einhorn LH; Loehrer PJ; Investigational new drugs 1992 Aug

Chemotherapy of male and female germ cell tumors.
Williams SD; Loehrer PJ; Nichols CR; Einhorn LN; Seminars in oncology 1992 Apr

High-dose carboplatin and etoposide with autologous bone marrow transplantation in refractory germ cell cancer: an Eastern Cooperative Oncology Group protocol.
Nichols CR; Andersen J; Lazarus HM; Fisher H; Greer J; Stadtmauer EA; Loehrer PJ; Trump DL; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992 Apr

Knowledge and beliefs about cancer in a socioeconomically disadvantaged population.
Loehrer PJ Sr; Greger HA; Weinberger M; Musick B; Miller M; Nichols C; Bryan J; Higgs D; Brock D; Cancer 1991 Oct 1

Randomized study of cisplatin dose intensity in poor-risk germ cell tumors: a Southeastern Cancer Study Group and Southwest Oncology Group protocol.
Nichols CR; Williams SD; Loehrer PJ; Greco FA; Crawford ED; Weetlaufer J; Miller ME; Bartolucci A; Schacter L; Einhorn LH; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991 Jul

Etoposide therapy for testicular cancer.
Loehrer PJ Sr; Cancer 1991 Jan 1

High dose carboplatin/VP-16 plus ifosfamide with autologous bone marrow support in the treatment of refractory germ cell tumors.
Broun ER; Nichols CR; Tricot G; Loehrer PJ; Williams SD; Einhorn LH; Bone marrow transplantation 1991 Jan

Chemotherapy for advanced testicular cancer.
Fox EP; Loehrer PJ Sr; Hematology/oncology clinics of North America 1991 Dec

Salvage therapy in recurrent germ cell cancer.
Loehrer PJ Sr; Hematology/oncology clinics of North America 1991 Dec

Mediastinal yolk sac tumor. The Indiana University experience, 1976 to 1988.
Saxman S; Nichols CR; Williams SD; Loehrer PJ; Einhorn LH; The Journal of thoracic and cardiovascular surgery 1991 Dec

Phase II trial of daily oral etoposide in patients with advanced non-small cell lung cancer.
Saxman S; Loehrer PJ Sr; Logie K; Stephens D; Workman F; Scullin D; Einhorn LH; Ansari R; Investigational new drugs 1991 Aug

Clinical trials in cancer therapy: efforts to improve patient enrollment by community oncologists.
Fisher WB; Cohen SJ; Hammond MK; Turner S; Loehrer PJ; Medical and pediatric oncology 1991

Hepatic resection for disseminated germ cell carcinoma.
Goulet RJ Jr; Hardacre JM; Einhorn LH; Loehrer PJ; Jones JA; Donohue JP; Madura JA; Grosfeld JL; Annals of surgery 1990 Sep

Chemotherapy for advanced thymoma. Preliminary results of an intergroup study.
Loehrer PJ Sr; Perez CA; Roth LM; Greco A; Livingston RB; Einhorn LH; Annals of internal medicine 1990 Oct 1

Spindle cell tumors resected from male patients with germ cell tumors. A clinicopathologic study of 14 cases.
Ulbright TM; Michael H; Loehrer PJ; Donohue JP; Cancer 1990 Jan 1

Primary mediastinal nonseminomatous germ cell tumors. A modern single institution experience.
Nichols CR; Saxman S; Williams SD; Loehrer PJ; Miller ME; Wright C; Einhorn LH; Cancer 1990 Apr 1

Ifosfamide in testicular cancer.
Loehrer PJ Sr; Seminars in oncology 1990 Apr

Cyclophosphamide and ifosfamide: role of uroprotective agents.
Williams SD; Munshi N; Einhorn LH; Loehrer PJ; Cancer investigation 1990

Management of postchemotherapy residual mass in patients with advanced seminoma: Indiana University experience.
Schultz SM; Einhorn LH; Conces DJ Jr; Williams SD; Loehrer PJ; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989 Oct

Ifosfamide plus doxorubicin in metastatic adult sarcomas: a multi-institutional phase II trial.
Loehrer PJ Sr; Sledge GW Jr; Nicaise C; Usakewicz J; Hainsworth JD; Martelo OJ; Omura G; Braun TJ; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989 Nov

Evaluation of optimal duration of chemotherapy in favorable-prognosis disseminated germ cell tumors: a Southeastern Cancer Study Group protocol.
Einhorn LH; Williams SD; Loehrer PJ; Birch R; Drasga R; Omura G; Greco FA; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989 Mar

Dose-intensive chemotherapy in refractory germ cell cancer--a phase I/II trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation.
Nichols CR; Tricot G; Williams SD; van Besien K; Loehrer PJ; Roth BJ; Akard L; Hoffman R; Goulet R; Wolff SN; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989 Jul

Ifosfamide in testicular cancer: the Indiana University experience.
Loehrer PJ Sr; Williams SD; Einhorn LH; Seminars in oncology 1989 Feb

Disseminated testicular cancer: current chemotherapy strategies.
Williams SD; Loehrer PJ; Nichols CR; Roth BJ; Einhorn LH; Seminars in oncology 1989 Aug

Salvage therapy in recurrent germ cell cancer: ifosfamide and cisplatin plus either vinblastine or etoposide.
Loehrer PJ Sr; Lauer R; Roth BJ; Williams SD; Kalasinski LA; Einhorn LH; Annals of internal medicine 1988 Oct 1

Testicular cancer: the quest continues.
Loehrer PJ Sr; Williams SD; Einhorn LH; Journal of the National Cancer Institute 1988 Nov 2

Cisplatin plus etoposide in small cell lung cancer.
Loehrer PJ Sr; Einhorn LH; Greco FA; Seminars in oncology 1988 Jun

Choriocarcinoma-like lesions in patients with testicular germ cell tumors. Two histologic variants.
Ulbright TM; Loehrer PJ; The American journal of surgical pathology 1988 Jul

Cisplatin as first-line therapy for metastatic breast cancer.
Sledge GW Jr; Loehrer PJ Sr; Roth BJ; Einhorn LH; Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1988 Dec

Etoposide and split-dose cisplatin in bronchogenic carcinoma.
Lauer RC; Fisher WB; Pennington K; Ansari R; Einhorn LH; Loehrer PJ; American journal of clinical oncology 1988 Dec

Chemotherapeutic approaches to the treatment of testicular cancer.
Seitz DE; Loehrer PJ Sr; Williams SD; Einhorn LH; Seminars in urology 1988 Aug

Salvage chemotherapy for lymphoma with VP-16, ifosfamide, and cisplatin.
Nichols CR; Loehrer PJ Sr; Greist A; Kubilis PS; Hoffman R; Medical and pediatric oncology 1988

Ifosfamide plus 5-fluorouracil for treatment of adenocarcinoma of the pancreas.
Loehrer PJ Sr; Williams SD; Nichols CR; Cancer treatment reports 1987 Nov

Status of chemotherapy for testis cancer.
Loehrer PJ Sr; Williams SD; Einhorn LH; The Urologic clinics of North America 1987 Nov
Professional Organizations

Alpha Omega Alpha Honor Medical Society

American Society of Clinical Oncology
Board Certifications

Oncology

American Board of Internal Medicine - Internal Medicine
Clinical Interests

Treatments in thymoma, GU (e.g. bladder cancer, testis cancer), GI cancer (e.g. pancreatic cancer, colon cancer, cancer).
Awards

Org: Indiana University
Desc: Distinguished Professor
Scope: University
Date: 1905-07-12

Org: American Society of Clinical Oncology
Desc: Allen S Lichter Visionary Leadership Award and Lecture
Scope: International
Date:

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