Faculty

Americo H. Lopez-Yglesias, PhD

Assistant Professor of Microbiology & Immunology

Email alopezyg@iu.edu

Phone (812) 237-3420

Address

Indiana University School of Medicine - Terre Haute
620 Chestnut Street, HH135

Terre Haute, IN 47809

Key Publications

1. ILC1s maintain IRF8+ dendritic cells via IFN-g during acute intracellular infection. López-Yglesias AH, Burger E, Camanzo E, Martin A, Araujo AM, and Yarovinsky F. bioRxiv, January, 2020

2. T-bet-independent Th1 response induces intestinal immunopathology during Toxoplasma gondii infection. López-Yglesias AH, Burger ES, Araujo A, Martin A, and Yarovinsky, F. Mucosal Immunology, 3 January 2018; doi:10.1038/mi.2017.102

3. Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathway. López-Yglesias AH, Zhao X, Quarles EK, Lai MA, VandenBos T, Strong RK, and Smith KD. Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathway. J. Immunology. 2014. Jan 17. 192: 0022-1767

View publications on Google Scholar

Titles & Appointments

Assistant Professor of Microbiology & Immunology

Education

2014 PhD University of Washington

2007 BS University of Washington
Research

Dr. López-Yglesias’ research program is characterizing how the transcription factor T-bet regulates the innate immune response against intracellular pathogens (Toxoplasma gondii, Salmonella) during acute infection. The lab uses transgenic mouse models to better understand how the complex interactions of the host-pathogen-microbiota impact innate immune cell effector function, intestinal tissue injury and immunity following oral infection with T. gondii or Salmonella, two leading causes of foodborne-related deaths in the United States.

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