Faculty

Robert S. Tepper, MD, PhD

Mary Agnes Kennedy and Katheryn Kennedy Weinberger Professor of Pediatrics

Phone (317) 274-9647

Address

705 Riley Hospital Drive
ROC 4270

Indianapolis, IN 46202

Bio

Dr. Tepper is the Mary Agnes Kennedy and Katherine Kennedy Weinberger Professor of Pediatrics at Indiana University School of Medicine. He is a graduate of University of Wisconsin Medical School and completed his pediatric residency at University of Wisconsin and pediatric pulmonary fellowship at University of Arizona. His research focuses on lung growth and development, lung disease very early in life, and translational research to minimize the effects of lung disease.

Titles & Appointments

Mary Agnes Kennedy and Katheryn Kennedy Weinberger Professor of Pediatrics
Adjunct Professor of Anatomy, Cell Biology & Physiology

Education

1983 Fellowship University of Arizona

1981 Residency University of Wisconsin

1978 PhD University of Wisconsin

1978 MD University of Wisconsin

1971 BS Columbia University
Research

Dr. Tepper’s research focuses upon lung structure and function as it relates to airway hyper-reactivity, as well as lung growth and maturation. Research studies focus upon 1) the effects of mechanical strain upon airway reactivity in vivo and in vitro, 2) the interaction between atopic inflammation and airway reactivity, and 3) the effect of Pak1 deficiency upon pulmonary inflammation and airway reactivity, and 4) the effects of premature birth, maternal smoking during pregnancy, and birth at high altitude (chronic hypoxia) on lung growth and development.
Publications

Vitamin C to Decrease the Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP): Rationale, design, and methods of a randomized, controlled trial of vitamin C supplementation in pregnancy for the primary prevention of effects of in utero tobacco smoke exposure on infant lung function and respiratory health.
McEvoy CT; Milner KF; Scherman AJ; Schilling DG; Tiller CJ; Vuylsteke B; Shorey-Kendrick LE; Spindel ER; Schuff R; Mitchell J; Peters D; Metz J; Haas D; Jackson K; Tepper RS; Morris CD; Contemporary clinical trials 2017 May 8

Effect of Continuous Positive Airway Pressure on Airway Reactivity in Asthma. A Randomized, Sham-controlled Clinical Trial.
Holbrook JT; Sugar EA; Brown RH; Drye LT; Irvin CG; Schwartz AR; Tepper RS; Wise RA; Yasin RZ; Busk MF; American Lung Association Airways Clinical Research Centers.; Annals of the American Thoracic Society 2016 Nov

Increased prevalence of airway reactivity in children with eosinophilic esophagitis.
Krupp NL; Sehra S; Slaven JE; Kaplan MH; Gupta S; Tepper RS; Pediatric pulmonology 2015 Oct 28

Pulmonary diffusing capacity in healthy African-American and Caucasian children.
Kim YJ; Christoph K; Yu Z; Eigen H; Tepper RS; Pediatric pulmonology 2015 Apr 23

Serum MicroRNA-21 as a Biomarker for Allergic Inflammatory Disease in Children.
Sawant DV; Yao W; Wright Z; Sawyers C; Tepper RS; Gupta SK; Kaplan MH; Dent AL; MicroRNA (Shariqah, United Arab Emirates) 2015

Exhaled nitric oxide during infancy as a risk factor for asthma and airway hyperreactivity.
Chang D; Yao W; Tiller CJ; Kisling J; Slaven JE; Yu Z; Kaplan MH; Tepper RS; The European respiratory journal 2014 Sep 26

An infant with pulmonary interstitial glycogenosis: clinical improvement is associated with improvement in the pulmonary diffusion capacity.
Ehsan Z; Montgomery GS; Tiller C; Kisling J; Chang DV; Tepper RS; Pediatric pulmonology 2013 Feb 8

Atopy, cytokine production, and airway reactivity as predictors of pre-school asthma and airway responsiveness.
Sarria EE; Mattiello R; Yao W; Chakr V; Tiller CJ; Kisling J; Tabbey R; Yu Z; Kaplan MH; Tepper RS; Pediatric pulmonology 2013 Feb 8

Increased lung volume in infants and toddlers at high compared to low altitude.
Llapur CJ; Martínez MR; Caram MM; Bonilla F; Cabana C; Yu Z; Tepper RS; Pediatric pulmonology 2013 Feb 8

Chorioamnionitis and subsequent lung function in preterm infants.
Jones MH; Corso AL; Tepper RS; Edelweiss MI; Friedrich L; Pitrez PM; Stein RT; PloS one 2013 Dec 5

Genetic variation in vascular endothelial growth factor-a and lung function.
Simpson A; Custovic A; Tepper R; Graves P; Stern DA; Jones M; Hankinson J; Curtin JA; Wu J; Blekic M; Bukvic BK; Aberle N; Marinho S; Belgrave D; Morgan WJ; Martinez FD; American journal of respiratory and critical care medicine 2012 Mar 29

Asthma outcomes: pulmonary physiology.
Tepper RS; Wise RS; Covar R; Irvin CG; Kercsmar CM; Kraft M; Liu MC; O'Connor GT; Peters SP; Sorkness R; Togias A; The Journal of allergy and clinical immunology 2012 Mar

Use of continuous positive airway pressure reduces airway reactivity in adults with asthma.
Busk M; Busk N; Puntenney P; Hutchins J; Yu Z; Gunst SJ; Tepper RS; The European respiratory journal 2012 Jul 26

Quantitative assessment of chronic lung disease of infancy using computed tomography.
Sarria EE; Mattiello R; Rao L; Tiller CJ; Poindexter B; Applegate KE; Granroth-Cook J; Denski C; Nguyen J; Yu Z; Hoffman E; Tepper RS; The European respiratory journal 2011 Oct 17

Pulmonary diffusing capacity in healthy Caucasian children.
Kim YJ; Hall GL; Christoph K; Tabbey R; Yu Z; Tepper RS; Eigen H; Pediatric pulmonology 2011 Nov 11

Computed tomography score and pulmonary function in infants with chronic lung disease of infancy.
Sarria EE; Mattiello R; Rao L; Wanner MR; Raske ME; Tiller C; Kimmel R; Tepper RS; The European respiratory journal 2011 Apr 8

Evaluation of airway reactivity and immune characteristics as risk factors for wheezing early in life.
Yao W; Barbé-Tuana FM; Llapur CJ; Jones MH; Tiller C; Kimmel R; Kisling J; Nguyen ET; Nguyen J; Yu Z; Kaplan MH; Tepper RS; The Journal of allergy and clinical immunology 2010 Sep

Growth of lung parenchyma in infants and toddlers with chronic lung disease of infancy.
Balinotti JE; Chakr VC; Tiller C; Kimmel R; Coates C; Kisling J; Yu Z; Nguyen J; Tepper RS; American journal of respiratory and critical care medicine 2010 Feb 4

Expired nitric oxide and airway reactivity in infants at risk for asthma.
Tepper RS; Llapur CJ; Jones MH; Tiller C; Coates C; Kimmel R; Kisling J; Katz B; Ding Y; Swigonski N; The Journal of allergy and clinical immunology 2008 Aug 28

Growth rate of lung function in healthy preterm infants.
Friedrich L; Pitrez PM; Stein RT; Goldani M; Tepper R; Jones MH; American journal of respiratory and critical care medicine 2007 Sep 20
Professional Organizations

American Academy of Pediatrics

American Lung Association

American Pediatric Society

American Physiological Society

American Thoracic Society

Society for Pediatric Research
Board Certifications

American Board of Pediatrics - Pediatrics

American Board of Pediatrics - Pediatric Pulmonology
Clinical Interests

Dr. Tepper’s clinical interests are infants with lung disease early in life.
Awards

Org: Alpha Omega Alpha Medical Honor Society
Desc: Alpha Omega Alpha
Scope: National
Date:

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