Research on Alzheimer’s disease at Indiana University School of Medicine encompasses the full spectrum of medical research—basic and preclinical, translational and population science. Faculty investigators studying Alzheimer’s disease have a strong and long-standing commitment to neurodegenerative research and receive generous grant awards and international support to advance their studies. IU School of Medicine is committed to ending the suffering of this disease no matter how long it takes.
Alzheimer’s Disease Research
Support Alzheimer’s disease research
Generous financial giving supports groundbreaking research and empowers scientists to fulfill their vision to end patient suffering. To discuss giving options, contact the Office of Gift Development.
Stark Neurosciences Research Institute
With a strong history of institutional commitment to neurosciences, IU School of Medicine is home to a uniquely connected campus of clinical, research and training space.
Alzheimer's disease research objectives
Understand what causes dementiaEven after decades of research, very little is known about what goes wrong in a person’s DNA to cause dementia. Researchers in basic science are working to analyze data and identify the root causes of dementia. Without this understanding, scientists can’t begin to formulate effective solutions.
Detect the disease earlyPhysician scientists now know that Alzheimer’s disease begins to develop about 20 years prior to the onset of dementia. The current thinking is that available treatments have largely been unsuccessful because the disease is too advanced when they are administered. Investigators at IU School of Medicine envision that Alzheimer’s disease will one day be screened for routinely, just as cholesterol tests are regularly administered to detect potential heart problems decades before a heart attack may occur.
Slow and prevent Alzheimers diseaseIU School of Medicine has played a major role in bringing some of today’s most commonly prescribed drugs to market—and continues to be a frontrunner in the development and testing of new drugs. Scientists are searching for new potential targets, developing new molecules and testing new interventions. Along with novel drugs, research teams are evaluating lifestyle interventions, including exercise and cognitive training, to slow or prevent dementia.
Improve the quality of life for patients and caregiversResearchers at IU School of Medicine study ways to improve the quality of life for both patients and caregivers. Across the United States, more than 15 million people are caring for a family member or close friend suffering from dementia. Although being a caregiver can be rewarding, it can also create physical, emotional and financial burdens.
Expertise and collaboration across the research spectrum
At IU School of Medicine, collaboration is key to solving Alzheimer’s disease and related dementias. Interdisciplinary research teams share resources and facilities that enable interaction and innovation. Several departments, the Indiana Alzheimer Disease Center and Stark Neurosciences Research Institute foster and facilitate the basic, translational and population science programs at IU School of Medicine.
A unique national resource
Faculty researchers studying Alzheimer’s disease at IU School of Medicine are recognized national leaders in the advancement of basic science, diagnostic imaging, immunotherapy, drug discovery and genetics research. Together, these molecular, genetic and imaging-based approaches to disease discovery and treatment can enable physician scientists throughout the world to advance understanding of Alzheimer's disease and its progression.
Alzheimer’s disease researchers study gene associated with the brain’s immune cells
IU School of Medicine | Jan 05, 2023